Amit Joshi, Wolfgang
Bangerth, Kildong Hwang, John C. Rasmussen, Eva
M. Sevick-Muraca
Plane wave fluorescence tomography with
adaptive finite elements
Optics Letters, vol. 31 (2006), pp. 193-195.
We present three dimensional fluorescence yield tomography of a
tissue phantom in a non-contact reflectance imaging setup. The method
employs planar illumination with modulated light and frequency
domain fluorescence measurements made on the illumination plane. An
adaptive finite element algorithm is
used to handle the ill-posed and computationally demanding
inverse image reconstruction problem. Tomographic images of
fluorescent targets buried at 1$cm$ to 2$cm$ depths from the
illumination surface demonstrate the feasibility of fluorescence
tomography from reflectance tomography in clinically relevant
tissue volumes.
Wolfgang Bangerth
Sun Mar 3 06:42:12 MST 2024