Speaker:
Liming Wang,
California State University at Los Angeles
Title:
Noise Attenuation in Feedback Systems
Abstract:
Feedback modules, which appear ubiquitously in biological
regulations, are often subject to disturbances from the input,
leading to fluctuations in the output. What are the functions
of feedback loops? Why are there often multiple feedback loops
in biological systems? Do they affect a system's noise
property? In this talk, we will explore these questions by
introducing a critical quantity: SAT (the signed activation time)
that dictates the noise attenuation capability in feedback
systems. Our findings suggest that the relationship between
the noise amplification rate and SAT could be a general principle
for many biological systems regardless of specific regulations or
feedback loops.